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The stage is set for a intriguing top-flight matchup as league leaders Arsenal entertain bottom-placed Wolverhampton Wanderers to the Emirates Stadium.

Confirmed Sides

Mikel Arteta's side have opted for three changes from the side that suffered a narrow loss at Aston Villa last weekend. William Saliba, Viktor Gyökeres and Gabriel Martinelli are all included in the lineup. The captain and Mikel Merino are named on the substitutes' bench, while Riccardo Calafiori is absent. Saliba returns after missing a run of games due to injury.

Wolves also have made three adjustments to their starting XI following being skelped 4-1 at Molineux by Manchester United on Monday evening. The experienced full-back, the Brazilian midfielder and Hwang Hee-chan start. Ki-Jana Hoever and Jhon Arias are on the bench, while Jean‐Ricner Bellegarde is omitted altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Substitutes: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Substitutes: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Match Official: Robert Jones
Video Assistant Referee: John Brooks

The Setup

Good evening! Because, let's be honest …

The table tells a striking story. The hosts sit comfortably at the pinnacle of the table, while their opponents anchor the league.

… however, even though this will be the 42nd occasion the Premier League leaders have faced the team at the foot of the division – with 30 out of 41, with seven tied games – who are responsible for two of the four all-time upsets? Why, Wolves, of course! So while the Arsenal manager will undoubtedly be expecting another three points, the Wolves boss must know that long shots occasionally succeed, and you never know. The start is at 8 o'clock in the evening GMT. Let's go!

^{(The other two bottom-beats-top wins in the Premier League era are Oldham Athletic's 1-0 win over United in March 1993, and Spurs – admittedly, this one sounds a bit weird - beating Liverpool in November 2008.)}